[1]王志龙,林文俐,杜贞华,等.微波消融联合经皮骨成形术在椎外溶骨性转移瘤中的应用 [J].介入放射学杂志,2023,32(06):580-585.
 WANG Zhilong,LIN Wenli,DU Zhenhua,et al.Application of microwave ablation combined with percutaneous osteoplasty in treating extraspinal osteolytic metastases[J].journal interventional radiology,2023,32(06):580-585.
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微波消融联合经皮骨成形术在椎外溶骨性转移瘤中的应用

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年06
页码:
580-585
栏目:
临床研究
出版日期:
2023-06-28

文章信息/Info

Title:
Application of microwave ablation combined with percutaneous osteoplasty in treating extraspinal osteolytic metastases
作者:
王志龙 林文俐 杜贞华 张晓帆 梁逸宁 左太阳
Author(s):
WANG Zhilong LIN Wenli DU Zhenhua ZHANG Xiaofan LIANG Yining ZUO Taiyang.
Department of Oncology Intervention, Affiliated Central Hospital of Shandong First Medical University, Jinan, Shandong Province 250013, China
关键词:
【关键词】 微波消融术 经皮骨成形术 椎体外溶骨性转移瘤安全性疗效
文献标志码:
A
摘要:
【摘要】 目的 观察CT引导下微波消融(MWA)联合经皮骨成形术(POP)治疗椎体外溶骨性转移瘤的疗效与安全性。方法 回顾性分析接受MWA联合POP治疗18例椎体外溶骨性转移瘤患者的临床资料。采用疼痛视觉模拟量表(visual analogue scale,VAS)、国际肌肉骨骼肿瘤学会(musculo- skeletal tumor society system,MSTS)评分、骨转移患者生活质量特异性量表(QLQ- BM22)评估患者手术前后疼痛程度、肢体功能状态和生活质量;记录手术成功率和术中、术后并发症情况,并对随访期间患者局部肿瘤控制状况和生存期进行统计分析。 结果 18例患者的MWA联合POP手术均成功。术中 4例患者出现少量骨水泥渗漏,均无明显症状。手术前后VAS评分总体差异有统计学意义(F=41.74,P<0.01);术后各时间点VAS评分均低于术前(均P<0.01),而术后各时间点间差异均无统计学意义(均P>0.05)。手术前后MSTS评分总体差异有统计学意义(F=12.40,P<0.01);术后各时间点MSTS评分均高于术前(均P<0.01),而术后各时间点间差异均无统计学意义(均P>0.05)。手术前后QLQ- BM22评分总体差异有统计学意义(F=16.26,P<0.01);术后各时间点QLQ- BM22评分均低于术前(均P<0.01),而术后各时间点间差异均无统计学意义(均P>0.05)。术后随访3~28个月,生存时间为(9.14±7.94)个月。随访期间死亡7例,6例术后1年内死亡,1例术后26个月死亡。3例患者分别于术后8、15、16个月肿瘤复发,平均复发时间为13个月。结论 CT引导下MWA联合经皮骨成形术治疗椎体外溶骨性转移瘤并发症少,安全可行,能有效缓解疼痛,改善患者肢体功能,提高患者运动能力和生活质量,术后局部肿瘤复发率低且复发周期较长。

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备注/Memo

备注/Memo:
(收稿日期:2022- 04-13)
(本文编辑:新 宇)
更新日期/Last Update: 2023-06-26