[1]邱秀萍,张桔顺,蔡 仅,等.不同聚桂醇留置量在甲状腺囊肿硬化治疗中效果分析[J].介入放射学杂志,2024,33(01):69-73.
 QIU Xiuping,ZHANG Jushun,CAI Jin,et al.Different retained dosage of lauromacrogol within the thyroid cyst in the sclerotherapy of thyroid cysts: an analysis of the curative effect[J].journal interventional radiology,2024,33(01):69-73.
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不同聚桂醇留置量在甲状腺囊肿硬化治疗中效果分析()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年01
页码:
69-73
栏目:
临床研究
出版日期:
2024-01-31

文章信息/Info

Title:
Different retained dosage of lauromacrogol within the thyroid cyst in the sclerotherapy of thyroid cysts: an analysis of the curative effect
作者:
邱秀萍 张桔顺 蔡 仅 黄汝哨 陈 阳 涂 梅 李仕海 邱思花
Author(s):
QIU Xiuping ZHANG Jushun CAI Jin HUANG Rushao CHEN Yang TU Mei LI Shihai QIU Sihua.
Department of Endocrinology, Longyan Municipal First Hospital, Longyan, Fujian Province 364000, China
关键词:
【关键词】 甲状腺囊肿 聚桂醇 硬化治疗 留置量
文献标志码:
A
摘要:
【摘要】 目的 分析评价不同聚桂醇留置量行甲状腺囊肿硬化治疗的效果。方法 纳入2020年8月至2021年8月在龙岩市第一医院治疗的200例(200枚)甲状腺囊肿患者,随机分为聚桂醇抽尽组和聚桂醇留置量分别为囊液体积10%、20%、30%、50%组等5组,每组40例。术后1、3、6、12个月复查甲状腺彩色超声,观察分析囊肿硬化后囊腔体积变化、疗效、影响因素及不良反应。采用logistic回归分析影响术后疗效的因素。 结果 各组抽出液体均呈暗红色,均为囊性结节。术前囊腔体积为(20.43±5.86) cm3。各组手术前后囊腔体积变化显示,术后1个月与术前、术后3个月与术后1个月、术后6个月与术后3个月相比显著缩小(均P<0.05),术后12个月与术后6个月相比相当(P>0.05)。术后6个月各组总有效率为87%(174/200),各组间术后6个月疗效差异无统计学意义(P>0.05)。以术后6个月疗效为因变量,年龄、性别、厚囊壁、囊腔分隔、术前囊腔体积等为自变量,进行二分类logistic回归分析,结果显示厚囊壁(OR=0.24,95%CI=0.08~0.72,P=0.01)、囊腔分隔(OR=0.21,95%CI=0.07~0.67,P=0.01)是影响术后6个月疗效的因素。各组不良反应主要为疼痛,均可忍受,各组不良反应发生率差异无统计学意义(均P>0.05)。结论 超声导引下聚桂醇硬化治疗甲状腺囊肿与聚桂醇留置量无关,术后6个月疗效最佳,可作为最佳随访复查时间。厚囊壁及囊腔分隔是影响硬化治疗效果的主要因素。甲状腺囊肿聚桂醇硬化治疗效果确切,不良反应少,值得临床推广应用。

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备注/Memo

备注/Memo:
(收稿日期:2022- 11- 28)
(本文编辑:谷 珂)
更新日期/Last Update: 2024-01-30