[1]林 燕,史瑶平,汤晓寅,等.超声引导射频消融在较大乳腺纤维腺瘤治疗中的应用[J].介入放射学杂志,2023,32(06):560-564.
 LIN Yan,SHI Yaoping,TANG Xiaoyin,et al.The application of ultrasound-guided radiofrequency ablation in the treatment of large breast fibroadenoma[J].journal interventional radiology,2023,32(06):560-564.
点击复制

超声引导射频消融在较大乳腺纤维腺瘤治疗中的应用()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年06
页码:
560-564
栏目:
非血管介入
出版日期:
2023-06-28

文章信息/Info

Title:
The application of ultrasound-guided radiofrequency ablation in the treatment of large breast fibroadenoma
作者:
林 燕 史瑶平 汤晓寅 丁 敏 何 意 李 萍 翟 博
Author(s):
LIN Yan SHI Yaoping TANG Xiaoyin DING Min HE Yi LI Ping ZHAI Bo.
Affiliated Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
关键词:
【关键词】 乳腺纤维腺瘤 夹心液体隔离技术 射频消融
文献标志码:
A
摘要:
【摘要】 目的 探讨超声引导夹心水隔离技术辅助的射频消融(RFA)在较大乳腺纤维腺瘤(直径≥2 cm)治疗中的应用价值。方法 选择2014年 12月至 2021年 3月上海交通大学医学院附属仁济医院治疗的乳腺纤维腺瘤患者39例。患者均接受超声引导夹心水隔离技术辅助的RFA治疗,观察消融前、消融后即刻、消融后1个月、消融后3个月、消融后6个月肿瘤体积变化以及肿瘤体积缩小率,RFA后并发症发生情况。结果 39 例患者(42个肿瘤)的RFA治疗时间为(176.7±116.6)s。治疗前肿瘤最大直径为2.0~3.4 cm,消融前、消融后即刻、消融后1个月、消融后3个月、消融后6个月肿瘤体积分别为(3.16±2.08) mL、(2.19±1.42) mL、(1.24±0.93) mL、(0.64±0.59) mL、(0.26±0.31) mL,治疗后1、3、6个月超声检查显示肿瘤体积较消融前逐渐缩小,体积缩小率分别为(48.3± 17.6)%、(77.8 ±17.1)%、(84.6± 17.4)%。治疗后12个月36个肿瘤消融区消失,6个肿瘤仍可见消融区痕迹。39例患者均无严重治疗相关并发症发生。结论 超声引导夹心水隔离技术辅助的RFA治疗直径≥2 cm的乳腺纤维腺瘤安全、微创、有效,适用于无法接受手术治疗的较大乳腺纤维腺瘤患者。

参考文献/References:

[1] Ackerman LV,Mucciardi AN,Gose EE,et al. Classification of benign and malignant breast tumors on the basis of 36 radiographic properties[J]. Cancer, 1973, 31: 342-352.
[2] Carty NJ,Carter C,Rubin C,et al. Management of fibroadenoma of the breast[J]. Ann R Coll Surg Engl, 1995, 77: 127- 130.
[3] Yelland A,Gazet JC,Coombes RC. Conservative management of fibroadenoma of the breast[J]. Br J Surg, 1996, 83: 1653.
[4] Jang JY,Kim SM,Kim JH,et al. Clinical significance of interval changes in breast lesions initially categorized as probably benign on breast ultrasound[J]. Medicine(Baltimore), 2017, 96: e6415.
[5] Dyrstad SW,Yan Y,Fowler AM,et al. Breast cancer risk associated with benign breast disease: systematic review and meta- analysis[J]. Breast Cancer Res Treat, 2015, 149: 569- 575.
[6] Meloni GB,Dessole S,Becchere MP,et al. Ultrasound- guided mammotome vacuum biopsy for the diagnosis of impalpable breast lesions[J]. Ultrasound Obstet Gynecol, 2001, 18: 520- 524.
[7] Jiang Y,Lan H, Ye Q, et al. Mammotome ?誖 biopsy system for the resection of breast lesions: clinical experience in two high- volume teaching hospitals[J]. Exp Ther Med, 2013, 6: 759- 764.
[8] Pan S,Liu W,Jin K,et al. Ultrasound- guided vacuum- assisted breast biopsy using mammotome biopsy system for detection of breast cancer: results from two high volume hospitals[J]. Int J Clin Exp Med, 2014, 7: 239- 246.
[9] Luo HJ,Chen X,Tu G,et al. Therapeutic application of ultrasound- guided 8- gauge mammotome system in presumed benign breast lesions[J]. Breast J, 2011, 17: 490- 497.
[10] Tavares ECA,Freitas S,Portilha A,et al. Efficacy and safety of percutaneous radiofrequency thermal ablation in the treatment of lung cancer lesions[J]. Acta Med Port, 2015, 28: 63- 69.
[11] Kitchin D,Lubner M, Ziemlewicz T,et al. Microwave ablation of malignant hepatic tumours: intraperitoneal fluid instillation prevents collateral damage and allows more aggressive case selection[J]. Int J Hyperthermia, 2014, 30: 299- 305.
[12] Meyer J,Toomay S.Update on treatment of liver metastases: focus on ablation therapies[J]. Curr Oncol Rep, 2015, 17: 420.
[13] 程 芳,王立平,徐 栋. 超声引导下热消融治疗甲状腺良性大结节的临床应用价值[J]. 介入放射学杂志, 2021, 30:364- 367.
[14] Cui R,Wu H,Xu J,et al. Volume reduction for≥2 cm benign breast lesions after ultrasound- guided microwave ablation with a minimum 12- month follow- up[J]. Int J Hyperthermia, 2021, 38: 341- 348.
[15] Li P,Tang XY T,Cui D,et al. Evaluation of the safety and efficacy of percutaneous radiofrequency ablation for treating multiple breast fibroadenoma[J]. J Cancer Res Ther, 2016, 12: C138- C142.
[16] 周 南. 乳腺良性病变微波消融治疗的现状与进展[J]. 中国微创外科杂志, 2020, 20:369- 372.
[17] 于 杰,梁 萍. 微波与射频消融的技术现状和肝癌临床治疗对比[J]. 医学研究杂志, 2008, 37:21- 24.
[18] Cao J,Fan P,Wang F,et al. Application of contrast- enhanced ultrasound in minimally invasive ablation of benign thyroid nodules[J]. J Interv Med, 2022, 5: 32- 36.
[19] Zhang W,Li JM,He W,et al. Ultrasound- guided percutaneous microwave ablation for benign breast lesions: evaluated by contrast- enhanced ultrasound combined with magnetic resonance imaging[J]. J Thorac Dis, 2017, 9: 4767- 4773.

备注/Memo

备注/Memo:
(收稿日期:2022- 06- 06)
(本文编辑:新 宇)
更新日期/Last Update: 2023-06-26