[1]钟 灼,高 飞,邱振康,等.“双夹心法”碳酸氢钠联合TACE治疗巨块型肝癌研究[J].介入放射学杂志,2022,31(01):83-87.
 ZHONG Zhuo,GAO Fei,QIU Zhenkang,et al.TACE combined with “double sandwich method” infusion of sodium bicarbonate for the treatment of massive hepatocellular carcinoma[J].journal interventional radiology,2022,31(01):83-87.
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“双夹心法”碳酸氢钠联合TACE治疗巨块型肝癌研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
31
期数:
2022年01
页码:
83-87
栏目:
临床研究
出版日期:
2022-01-25

文章信息/Info

Title:
TACE combined with “double sandwich method” infusion of sodium bicarbonate for the treatment of massive hepatocellular carcinoma
作者:
钟 灼 高 飞 邱振康 龙 德
Author(s):
ZHONG Zhuo GAO Fei QIU Zhenkang LONG De.
Department of Oncology, Guangzhou Municipal Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, Guangdong Province 510800, China
关键词:
【关键词】 巨块型肝癌 TACE 碳酸氢钠 双夹心法
文献标志码:
A
摘要:
【摘要】 目的 探讨“双夹心法”碳酸氢钠联合TACE在巨块型肝癌中的应用价值。方法 按照标准纳入60例巨块型肝癌患者进行临床研究,采取TACE 治疗30例为对照组,“双夹心法”碳酸氢钠联合TACE治疗30例为研究组,均行每月1次共3个周期TACE治疗,期间动态评估疗效、生存质量、不良反应及血气pH值。结果 虽然对照组疾病稳定率(SD)好于研究组(P<0.05),但研究组治疗后客观缓解率(ORR)、部分缓解率(PR)、甲胎蛋白(AFP)下降幅度、KPS评分均好于对照组(P<0.05),且肝功能损伤及临床不良反应两组差异无统计学意义(P>0.05)。研究组治疗后血气PH值较对照组升高,但均在正常可控范围内,未对患者预后带来不良影响。结论 “双夹心法”碳酸氢钠联合TACE在巨块型肝癌治疗中疗效良好,无严重不良反应,可作为临床治疗方法之一。

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备注/Memo

备注/Memo:
(收稿日期:2020- 11- 24)

(本文编辑:俞瑞纲)
更新日期/Last Update: 2022-01-12