[1]王立静,苗同国,宁更献,等.肝动脉化疗栓塞术对原发性肝癌患者T淋巴细胞亚群的影响 [J].介入放射学杂志,2015,(02):165-168.
　WANG Li jing,MIAO Tong guo,NING Geng xian,et al.The influence of TACE on T lymphocyte subsets in patients with primary liver cancer[J].journal interventional radiology,2015,(02):165-168.
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肝动脉化疗栓塞术对原发性肝癌患者T淋巴细胞亚群的影响 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2015年02期
页码:
165-168
栏目:
临床研究
出版日期:
2015-02-25

文章信息/Info

Title:
The influence of TACE on T lymphocyte subsets in patients with primary liver cancer
作者:
王立静;  苗同国;  宁更献;  张建集;  蔡丽芬
Author(s):
WANG Li jing;  MIAO Tong guo;  NING Geng xian;  ZHANG Jian ji;  CAI Li fen.
Intensive Care Unit， Fifth Hospital of Shijiazhuang， Shijiazhuang， Hebei Province 050000， China
关键词:
【关键词】　 原发性肝癌;  肝动脉化疗栓塞术;  T细胞亚群;  细胞免疫功能
文献标志码:
A
摘要:
【摘要】　 目的　 探讨肝动脉化疗栓塞术（TACE）前后原发性肝癌（PHC）患者T 细胞亚群的变化。方法 　采用流式细胞术（FCM）检测PHC患者TACE术前1 d与术后1、2、3和4周外周血CD3、CD4、CD8 T细胞及CD4/CD8、CD4CD25/CD4的比值变化。结果　 PHC患者术前外周血T细胞亚群CD3、CD4、CD4/CD8比值显著低于健康对照组，CD8则明显高于健康对照组（P < 0.05）；治疗1周后外周血T细胞亚群指标较治疗前明显下降（P < 0.05），而4周后外周血T细胞亚群CD3、CD4、CD8及 CD4/CD8比值较治疗前显著增高（P < 0.05）。PLC患者外周血中CD4CD25/CD4 T细胞的比例显著高于健康对照组，与术前比较，术后1、2周外周血CD4CD25/CD4 T细胞的比例明显升高，术后4周外周血CD4CD25/CD4 T细胞的比例显著下降。结论　 TACE可以改善PHC患者的免疫状况。

参考文献/References:

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备注/Memo

备注/Memo:
（收稿日期：２０１4-０8-12）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2015-02-16