[1]金晶,翟仁友,高黎,等.金属内支架胆管引流与放射治疗结合治疗肝外胆管癌[J].介入放射学杂志,2007,(10):699.
 JIN Jing,ZHAI Ren-you,GAO Li,et al.Outcome of self-expanding metal stenting followed by radiation therapy for unresectable extrahepatic bile duct cancer[J].journal interventional radiology,2007,(10):699.
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金属内支架胆管引流与放射治疗结合治疗肝外胆管癌()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年10期
页码:
699
栏目:
临床研究
出版日期:
2007-10-15

文章信息/Info

Title:
Outcome of self-expanding metal stenting followed by radiation therapy for unresectable extrahepatic bile duct cancer
作者:
金晶翟仁友高黎
100021北京中国医学科学院中国协和医科大学肿瘤研究所肿瘤医院放疗科(金晶、高黎、余子豪、韩嘉珠);首都医科大学附属北京朝阳医院放射科(翟仁友)
Author(s):
JIN JingZHAI Ren-youGAO LiYU Zi-haoHAN Jia-zhu.
Department of Radiation Oncology,Cancer Institute(Hospital),Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing100021,China
关键词:
肝外胆管癌放射治疗近距离治疗金属内支架
分类号:
R735.8
文献标志码:
B
摘要:
目的回顾性分析局部晚期肝外胆管癌金属内支架胆管引流结合放射治疗的疗效。方法1996年1月至2002年9月收治17例不能手术切除肝外胆管癌患者,先接受金属支架行胆管引流,3例治疗1周内失访,其余14例单纯近距离放疗(近距离照射组,n=5)或外照射(外照射组,n=9,其中包括2例近距离+外照射)。Ir 192 高剂量率近距离放疗在金属内支架置入当天或隔天治疗。外照射的中位剂量48Gy(14~66Gy),2Gy/次。结果经金属内支架置入结合放疗后,10例黄疸患者中8例黄疸消褪,近距离和外照射对缓解黄疸症状无显著差别。全组中位生存期12个月(5~35个月),1、2年生存率分别为40.8%和8.2%。近距离治疗组与体外照射组的中位生存期、1、2年生存率分别为8个月、40.0%、20.2%和12个月、40.0%、13.3%(χ 2 =1.10,P=0.29)。结论金属内支架胆管引流结合放射治疗可以显著缓解黄疸症状,高剂量放射治疗可以进一步提高长期生存。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2007-03-06
基金项目:国家十一五课题资助项目(2007BAI05B06)
更新日期/Last Update: 2007-10-15